1. The following are true about DNA synthesis:
a. it requires DNA polymerase
b. reverse transcriptase enzymes are involved
c. moves in a 5'--->
3' direction
d. the rate of error in DNA synthesis is 1 in 105
base pairs
e. cytarabine inhibits DNA synthesis
2. With regard to DNA molecules:
a. they contain adenine, cytosine, guanine and
uracil bases
b. they can be detected with Western blotting
c. they can be detected with Southern blotting
d. they are denatured at temperature of 1000C
e. they are denatured by pH of £
7.14
3. G-proteins:
a. are activated by the binding of an extracellular
ligand to a membrane receptor
b. can be mutated in tumour cells
c. mediate the action of glucocorticoid hormone
d. they are inactivated by cholera toxins.
e. bind to DNA to regulate gene transcription
4. The following is true
about gluconeogenesis:
a. it occurs
in liver
b. it occurs in kidney
c. it occurs in adipose
tissue
d. it is inhibited
by glucagon
e. it is stimulated
by insulin
5. With regard
to membrane receptors for hormones:
a. they are
often glycoproteins
b. they are important
for hormones made up of steroid
c. those for insulin
exhibit an intrinsic protein kinase activity
d. glucagon uses calcium
as a second messenger
e. catecholamines
uses cyclic AMP as second messenger
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