Test 157  (Pharmacology )

1. The adrenal cortex produces:

a. aldosterone

b. angiotensin II

c. deoxycorticosterone

d. noradrenaline

e. adrenaline
 

Answera.T   b.F   c.T    d.F   e.F
Conversion of angiotensin I to II occurs in the lungs. Noradrenaline and adrenaline are produced by adrenal medulla.
 

2. With regard to thyroxine:

a. about 90% is protein bound

b. it is bound predominantly to albumin

c. it is important for skeletal growth

d. it increases the sensitivity of receptors to 
    catecholamines

e. it increases oxygen consumption
 

Answera.F   b.F  c.T  d.T  e.T
Thyroxine is 99.98% protein bound. Although albumin has the largest capacity for binding thyroxine, globulins have the greater affinity for thyroxine. About 67% of protein bound thyroxine is bound to thyroxine-binding globulin.
 

3. The following chemicals can cause pain when applied directly to 
    the nerve endings:

a. histamine

b. serotonin

c. prostaglandins

d. bradykinin

e. potassium
 

Answer
a.T   b.T   c.F   d.F  e.T
Bradykinin and prostaglandins sensitize the nerve endings to pain but do not cause pain themselves.
 

4. Acetylcholinesterase inhibitors include:

a. physostigmine

b. ecothiopate

c. edrophonium

d. pyridostigmine

e. malathion

Answer
a.T   b.T c.T  d.T  e.T
 

5. Acetylcholine is the chemical mediator released at the following sites:

a. parasympathetic preganglionic neurones

b. sympathetic preganglionic neurones 

c. parasympathetic postganglionic neurones

d. sympathetic postganglionic neurones

e. postganglionic sympathetic neurones that innervate the 
    sweat glands
 

Answer
a.T   b.T  c.T   d.F  e.T
Noradrenaline is secreted at the sympathetic postganglionic neurones.

 

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