Test 153  (Pharmacology )

1. Protein binding is affected by:

a. pregnancy

b. pH

c. liver disease

d. renal disease

e. age of the patients
 

Answera.T   b.T   c.T    d.T   e.T

2. Atropine:

a. inhibits the eccrine sweat glands

b. reverses the miosis caused by opioids

c. causes hyperpyrexia in overdose

d. crosses the blood brain barrier readily

e. is more sedative than hyoscine
 

Answera.T   b.T  c.T  d.T  e.F
Atropine is less sedative than hyoscine.

3. Nitric oxide:

a. forms toxic gases when combined with oxygen

b. inhibits platelet aggregation

c. is rapidly inactivated by haemoglobin when it enters the 
    circulation.

d. causes pulmonary vasodilatation

e. is also known as endothelium relaxing factor
 

Answer
a.T   b.T   c.T   d.T  e.T
Nitric oxide combines with oxygen to 
form nitric dioxide which is toxic.

4. The following muscarinic agonists are structurally related 
    acetylcholine:

a. pilocarpine

b. carbachol

c. methacholine

d. arecoline

e. aceclidine

Answer
a.F   b.T c.T  d.F  e.F
Pilocarpine and aceclidine are natural alkaloids and arecoline and aceclidine is a synthetic analog.

 

5. The effects of muscarinic agonists include:

a. reduced intraocular pressure

b. reduced aqueous production

c. accommodative myopia

d. increased lacrimation

e. contraction of the pupillary sphincter muscle
 

Answer
a.T   b.F  c.T   d.T  e.T
Muscarinic agonists reduces intraocular pressure 
by increasing the outflow. The aqueous production
is not affected. Miosis occurs due to contraction of the pupillary sphincter muscle.

 

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