Test 106   (Miscellaneous)

1. Drugs that are bacteriostatic include: 

a. rifampicin

b. fusidic acid

c. sulphodimidin

d. chloramphenicol

e. tetracyclines

Answera.F  b.F  c.T  d.T  e.T
Bacteriostatic agents inhibit bacterial replication and do not kill the organisms (cf. with bactericidal)..
 

2. With regard to iron in the human body:

a. it is stored chiefly in the bone marrow

b. 70% of iron in the body is found in the haemoglobin

c. it is transported in the body as transferrin

d. it is absorbed mainly in the ferric form

e. the liver excretes excess iron

Answera.F   b.T   c.T   d.F  e.F
Iron is stored mainly in the ferritin.
It is absorbed mainly in the ferrous form.
Excess iron is excreted into the intestinal lumen through shedding of the mucosal cells which bind excess iron.

 
3. The bioavailability of an orally administered drug depends on:

a. first pass metabolism

b. water solubility

c. lipid solubility

d. dose of the drug

e. presence of other drugs in the alimentary system

Answera.T   b.T  c.T  d.F  e.T
The bioavailability of a drug refers to the percentage of that drug available in the body after administration. 
It is expressed as a percentage on the assumption
that intravenous administration provides 100% bioavailability.
Bioavailability may be different with different pharmaceutical formulations of the same drug. Extensive first pass metabolism or poor absorption give low bioavailability.

4. With regard to monosynaptic reflex:

a. the reflex originates and terminates in the same muscle

b. the reflex is very fast measuring about 20 milliseconds

c. knee jerk response is a monosynaptic reflex 

d. withdrawal of hand in response to pain is a 
    monosynaptic reflex

e. corneal reflex is a monosynaptic reflex

Answera.T  b.T  c.T  d.F  e.F
Withdrawal of hand in response to pain and corneal reflex are polysynaptic reflexes.

5. Interruption of the cervical sympathetic chain causes:

a. hyperhydrosis

b. poor accommodation

c. nasal mucosal engorgement

d. wasting of the small hand muscle

c. complete ptosis

Answera.F  b.F  c.T  d.F  e.F
A lesion of the cervical sympathetic chain causes Horner's syndrome with miosis and partial ptosis. 
Anhydrosis and nasal mucosal engorgement are also seen.
Wasting of the small hand muscle results from T1 lesion.

 
 

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